Product Name :
TNPO3 Recombinant Rabbit Monoclonal Antibody [JG38-77]
Predicted band size :
Observed band size :
Synonyms:
TNPO 3 antibody Imp12 antibody Importin 12 antibody Importin-12 antibody IPO12 antibody MTR10A antibody TNPO3 antibody TNPO3_HUMAN antibody Transportin 3 antibody Transportin SR antibody 展开
Function :
The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human TNPO3 aa 830-923 / 923.5-Bromo-1,3-thiazole-2-carbaldehyde site
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P
Coupling :
unconjugated
Clone number:
JG38-77
RRID:
AB_3070874
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.204376-48-7 manufacturer Aliquot store at -20℃.PMID:33583227 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
104 kDa
Positive control :
K562 cell lysate, HL-60 cell lysate, mouse pancreas tissue lysate, A549, SH-SY5Y, SiHa, human liver carcinoma tissue, human small intestine tissue, mouse lung tissue, mouse kidney tissue.